A cost-effective solution to provide asphalt pavements with the photocatalytic property was addressed for the first time, based on the combination of low percentages of two semiconductors, TiO2 and ZnO. Two photocatalytic techniques – spray deposition and bitumen modification – were used. With the former, the chemical properties were evaluated by FTIR after spraying the bitumen samples with two aqueous solutions, one with acid PH and another alkaline, of nano-TiO2. The solution with less chemical impact was the alkaline one. With the latter, Penetration, Softening Point, Mass Loss, Dynamic Viscosity, Complex moduli and Performance Grade, after the modification by TiO2nano/microparticles and ZnO microparticles, were analysed with two levels of ageing produced by the RTFOT. TiO2 nano/microparticles and ZnO microparticles conducted to softer bitumens and better results of short-term ageing resistance and did not cause any deterioration to the bitumen before or after either short- or long-term ageing.