Natural ventilation has served as an effective passive cooling design strategy to reduce energy used by air-conditioning systems. The correct utilization of natural ventilation beyond reduce the energy consumption, improve the thermal comfort of users. For better natural ventilation performance is important that shape and position of inlets and outlets ventilation openings be properly designed. For this purpose, wind tunnel tests are a reliable tool to determine the influence of natural ventilation in buildings, which is the specific objective of this research. Based on the importance of natural ventilation study for buildings, this paper presents results of wind tunnel measurement to evaluate the influence of different ventilation modules positioning on a façade system. The positioning of ventilation modules was modified in the façade configuration for evaluate the results in the average air velocity at specific points observed in a model. The tests were carried out for a model, varying the façade configuration. The cases tested were six ventilation modules positioned below the window-sill (ventilated window-sill), three ventilation modules positioned separately above and below the façade for modules. Wind speed measurements were taken inside and outside the model for the different façades configurations to evaluate the best performance in relation to natural ventilation. Results show the use of six ventilation modules positioned below the window-sill, forming a “ventilated window-sill” is the best solution in terms of natural ventilation.